The Use of Gemcitabine and Docetaxel as a Novel Combination for Hyperthermic Intraperitoneal Chemotherapy in the Management of Recurrent Complicated Abdominal Sarcoma: Case Report and Review of Literature

Abstract

Sarcoma is a rare mesenchymal tumor. Evaluation of sarcoma patients primarily or after recurrence must be done in an experienced center. En bloc surgical resection is the mainstay of treatment for all sarcoma subtypes. The primary surgery or re-resection after recurrence must be done by an experienced, well-trained surgeon. Correlation between the imaging findings, the operative, and the histopathological findings is a must. We report a patient who was diagnosed with retroperitoneal sarcoma and had three surgical resections with incomplete removal. The last resection was complicated by a urinary leak. The tumor was resected piecemeal with the use of gemcitabine and docetaxel as a novel combination for hyperthermic intraperitoneal chemotherapy in recurrent complicated abdominal sarcomas.

Keywords

• complicated abdominal sarcoma; gemcitabine and docetaxel; hyperthermic intraperitoneal chemotherapy; management; recurrent sarcoma