Analysis of adverse events following immunization of adsorbed acellular DPT vaccine at different vaccination sites

Abstract

ObjectiveTo analyze the occurrence of suspected adverse events following immunization （AEFI） after changing the priority vaccination sites of the adsorbed acellular diphtherior-pertussis-tetanus vaccine （hereinafter referred to as DPT vaccine）， so as to provide scientific basis for mass vaccination.MethodsMonitoring data of AEFI for the DPT vaccine in Wujiang District from September 2020 to August 2022 were collected from China's disease prevention and control information system， and the vaccination information of DPT vaccine in all children's vaccination clinics in Wujiang District during the same period was selected. The incidence of AEFI for the DPT vaccine was analyzed and compared.ResultsThe reported incidence of AEFI was significantly lower in the buttocks than that in other sites （P5.0 cm） in the deltoid muscle of the upper arm was significantly higher than that in the buttocks （P<0.05）.ConclusionThe DPT vaccine is safe in different parts of the body and is worth popularizing.

Keywords

• dpt vaccine
• adverse events following immunization
• inoculation site
• clinical symptom
• local redness and swelling