Sensitivity of Mycobacterium leprae to Telacebec

Abstract

The treatment of leprosy is long and complex, benefiting from the development of sterilizing, rapidly-acting drugs. Reductive evolution made Mycobacterium leprae exquisitely sensitive to Telacebec, a phase 2 drug candidate for tuberculosis. The unprecedented potency of Telacebec against M. leprae warrants further validation in clinical trials.

Keywords

• Hansen disease
• tuberculosis and other mycobacteria
• bacteria
• Mycobacterium leprae
• leprosy
• telacebec