First Total Synthesis of Cryptopyranmoscatone A3 and Crypto­pyranmoscatone B4

Abstract

Abstract The first total synthesis of cryptopyranmoscatones A3 and B4 has been accomplished from d-ribose or but-3-ynol. The key steps involved in the synthesis are oxa-Michael addition, highly diastereo­selective Brown allylation, and ring closing metathesis (RCM) and cross metathesis (CM) reactions.

Keywords

• oxa-michael addition
• brown asymmetric allylation
• ring-closing metathesis
• cross metathesis