Pharmaceutical Technology in Hospital Pharmacy (Apr 2022)

Long-term stability of ready-to-use epinephrine 0.02 mg/mL injection solution in 50 mL glass vials

  • Heeb Rita Marina,
  • Erdnüß Frank,
  • Reichhold Julia,
  • Krämer Irene

DOI
https://doi.org/10.1515/pthp-2021-0015
Journal volume & issue
Vol. 7, no. 1
pp. 798 – 9

Abstract

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In adult intensive care patients, epinephrine is mostly administered by continuous injection with syringe pumps. The objective of this study was to investigate the physicochemical stability of pharmacy prepared ready-to-use epinephrine (E) 0.02 mg/mL injection solutions (total volume 50 mL) for assigning shelf-life.

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