International Journal of Ophthalmology (Feb 2023)

Regional chemotherapy for uveal melanoma liver metastases

  • Yang-Xu Tao,
  • Hao-Wen Li,
  • Jing-Ting Luo,
  • Yang Li,
  • Wen-Bin Wei

DOI
https://doi.org/10.18240/ijo.2023.02.18
Journal volume & issue
Vol. 16, no. 2
pp. 293 – 300

Abstract

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Chemotherapy remains an important approach for the treatment of liver metastases from uveal melanoma (UM). Compared with systemic chemotherapy, regional chemotherapy has similar efficacy and fewer systemic adverse effects. Regional chemotherapy for UM liver metastases includes hepatic artery infusion (HAI), transarterial chemoembolization (TACE), and isolated hepatic perfusion (IHP). In this review, we aim to examine the efficacy of regional chemotherapy and compare HAI, TACE, and IHP in terms of overall survival (OS). The three approaches showed no obvious difference in OS results.

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