Role of CysI–CysIII Disulfide Bond on the Structure and Activity of α‑Conotoxins at Human Neuronal Nicotinic Acetylcholine Receptors

• Nargis Tabassum,
• Han-Shen Tae,
• Xinying Jia,
• Quentin Kaas,
• Tao Jiang,
• David J. Adams,
• Rilei Yu

Affiliations

Nargis Tabassum

Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China

Han-Shen Tae

Illawarra Health and Medical Research Institute (IHMRI), University of Wollongong, Wollongong, New South Wales, Australia

Xinying Jia

§The Centre for Advanced Imaging, The University of Queensland, Brisbane, Queensland, Australia

Quentin Kaas

∥Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia

Tao Jiang

Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China

David J. Adams

Illawarra Health and Medical Research Institute (IHMRI), University of Wollongong, Wollongong, New South Wales, Australia

Rilei Yu

Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China