Study protocol for a pragmatic randomised controlled trial comparing the effectiveness and cost-effectiveness of levetiracetam and zonisamide versus standard treatments for epilepsy: a comparison of standard and new antiepileptic drugs (SANAD-II)

• Girvan Burnside,
• Munir Pirmohamed,
• Anthony Guy Marson,
• John Paul Leach,
• Gus Baker,
• Catrin Tudur-Smith,
• Richard Appleton,
• Silviya Balabanova,
• Graeme Sills,
• Catrin Plumpton

Affiliations

Girvan Burnside

3 Clinical Trials Research Centre, The University of Liverpool, Liverpool, UK

Munir Pirmohamed

10 Department of Pharmacology, University of Liverpool Faculty of Health and Life Sciences, Liverpool, UK

Anthony Guy Marson

1 Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK

John Paul Leach

7 School of Medicine, University of Glasgow, Glasgow, UK

Gus Baker

1 Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK

Catrin Tudur-Smith

Institute of Translational Medicine, University of Liverpool Institute of Translational Medicine, Liverpool, UK

Richard Appleton

Department of Neurology, Alder Hey Children's NHS Foundation Trust, Liverpool, Merseyside, UK

Silviya Balabanova

1 Liverpool Clinical Trials Centre, University of Liverpool, Faculty of Health and Life Sciences, Liverpool, UK

Graeme Sills

2 School of Life Sciences, University of Glasgow, Glasgow, UK

Catrin Plumpton

4 Centre for Health Economics and Medicines Evaluation, Bangor University, Bangor, UK