Evolution of sequence-specific anti-silencing systems in Arabidopsis

Aoi Hosaka; Raku Saito; Kazuya Takashima; Taku Sasaki; Yu Fu; Akira Kawabe; Tasuku Ito; Atsushi Toyoda; Asao Fujiyama; Yoshiaki Tarutani; Tetsuji Kakutani

doi:10.1038/s41467-017-02150-7

Nature Communications (Dec 2017)

Evolution of sequence-specific anti-silencing systems in Arabidopsis

Aoi Hosaka,
Raku Saito,
Kazuya Takashima,
Taku Sasaki,
Yu Fu,
Akira Kawabe,
Tasuku Ito,
Atsushi Toyoda,
Asao Fujiyama,
Yoshiaki Tarutani,
Tetsuji Kakutani

Affiliations

Aoi Hosaka: Department of Integrated Genetics, National Institute of Genetics
Raku Saito: Department of Integrated Genetics, National Institute of Genetics
Kazuya Takashima: Department of Integrated Genetics, National Institute of Genetics
Taku Sasaki: Department of Integrated Genetics, National Institute of Genetics
Yu Fu: Department of Integrated Genetics, National Institute of Genetics
Akira Kawabe: Department of Bioresource and Environmental Sciences, Faculty of Life Sciences, Kyoto Sangyo University, Motoyama Kamigamo
Tasuku Ito: Department of Integrated Genetics, National Institute of Genetics
Atsushi Toyoda: Center for Information Biology, National Institute of Genetics
Asao Fujiyama: Center for Information Biology, National Institute of Genetics
Yoshiaki Tarutani: Department of Integrated Genetics, National Institute of Genetics
Tetsuji Kakutani: Department of Integrated Genetics, National Institute of Genetics

DOI: https://doi.org/10.1038/s41467-017-02150-7
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 10

Abstract

Read online

Eukaryotes often silence transposable elements (TEs) via DNA methylation. Here, the authors show that evolution of VANC, an Arabidopsis anti-silencing factor, and its target motifs allows sequence-specific demethylation, suggesting a way TEs can proliferate while minimizing damage to the host genome.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal