Electronic Proceedings in Theoretical Computer Science (Sep 2011)
A Study of the PDGF Signaling Pathway with PRISM
Abstract
In this paper, we apply the probabilistic model checker PRISM to the analysis of a biological system -- the Platelet-Derived Growth Factor (PDGF) signaling pathway, demonstrating in detail how this pathway can be analyzed in PRISM. We show that quantitative verification can yield a better understanding of the PDGF signaling pathway.