Archivos Latinoamericanos de Nutrición (Mar 2001)
<title language="eng">Bioavailability of iron bis-glycinate chelate in water
Abstract
Biodisponibilidad del hierro bis-glicinato quelado dado en agua. El hierro aminoácido quelado está siendo considerado en forma creciente para programas de fortificación de alimentos. La absorción del hierro del bisglicinato dado en agua the estudiada en un grupo de 14 mujeres utilizando la técnica doble isotópica. Las absorciones de soluciones acuosas de 15 mg/L de hierro elemental como bis-glicinato o como ascorbato ferroso no theron significativamente distintas (34,6% y 29,9% respectivamente). La absorción estandardizada del bis-glicinato de hierro the 46,3% (estandarizado a 40% absorción de la dosis de referencia de ascorbato ferroso). Existió una correlación significativa entre el logaritmo de la absorción del bis-glicinato y el logaritmo de la ferritina sérica (r= -0,60, p Iron amino acid chelate is being increasingly considered in programs for iron fortification of foods. The bioavailability of iron bis-glycinate chelate given in water was studied using a double-isotopic method in a group of 14 women. Iron absorption from aqueous solutions of 15 mg/L of elemental iron as either iron bis-glycine chelate or ferrous ascorbate was not significantly different (34.6% and 29.9% respectively). Standardized iron absorption of the iron bis-glycinate was 46.3% (standardized to 40% absorption of the reference dose). There was a significant correlations between (In) iron absorption of iron bis- glycinate chelate with (In) serum ferritin (r= -0.60, p <0.03) and with (In) iron absorption from ferrous ascorbate (r= 0.71, p<0.006), suggesting that iron bis-glycinate chelate absorption is indeed regulated by the iron stores of the body.
