Fisetin's Promising Antitumor Effects: Uncovering Mechanisms and Targeting for Future Therapies

Abstract

Background Cancer remains a critical global health challenge and a leading cause of mortality. Flavonoids found in fruits and vegetables have gained attention for their potential anti-cancer properties. Fisetin, abundantly present in strawberries, apples, onions, and other plant sources, has emerged as a promising candidate for cancer prevention. Epidemiological studies linking a diet rich in these foods to lower cancer risk have sparked extensive research on fisetin’s efficacy.

Keywords

• apoptosis
• autophagy
• cell cycle arrest
• fisetin