Utilização de α,α-Diclorociclobutanonas em Síntese de Produtos Naturais The utilization of α, α-dichlorocyclobutanones in the synthesis of natural products

Abstract

The preparation and chemical potentiality of a,a-dichlorocyclobutanones as useful intermediates in the total synthesis of natural products are reviewed. Some aspects related to the recent advances reported in the literature about the mechanism of [2+2] cycloaddition reaction between dichloroketene and olefins are also presented.

Keywords

• a,a-dichlorocyclobutanones
• dichloroketene
• cycloaddition reactions