Pathological and Molecular Features of Lung Micropapillary Adenocarcinoma

Abstract

Lung micropapillary adenocarcinoma is characterized by frequent metastasis, lymph node infiltration, high recurrence rate and low overall survival rate as a high-grade lung adenocarcinoma. Special oncogenic pathway is activated and immune microenvironment is established in this subtype of tumor. This article reviews the Pathological phenomena and molecular features of micropapillary adenocarcinoma studied in recent years, aiming to deepen the understanding of micropapillary lesions and lay the foundation for formulating specific treatment strategies.

Keywords

• micropapillary adenocarcinoma
• metastasis
• recurrence
• driver gene
• immune microenvironment