Overview and progress of X-nuclei magnetic resonance imaging in biomedical studies

Gengxin Wang; Hongyi Yang; Juan Li; Jie Wen; Kai Zhong; Changlin Tian

Magnetic Resonance Letters (Nov 2023)

Overview and progress of X-nuclei magnetic resonance imaging in biomedical studies

Gengxin Wang,
Hongyi Yang,
Juan Li,
Jie Wen,
Kai Zhong,
Changlin Tian

Affiliations

Gengxin Wang: Institutes of Physical Science and Information Technology, Anhui University, Hefei, 230601, China; Anhui Provincial Key Laboratory of High Field Magnetic Resonance Imaging, High Magnetic Field Laboratory, Hefei Institute of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China
Hongyi Yang: Anhui Provincial Key Laboratory of High Field Magnetic Resonance Imaging, High Magnetic Field Laboratory, Hefei Institute of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China
Juan Li: School of Life Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230026, China
Jie Wen: The First Affiliation Hospital, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230001, China
Kai Zhong: Anhui Provincial Key Laboratory of High Field Magnetic Resonance Imaging, High Magnetic Field Laboratory, Hefei Institute of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China; Division of Medicine, Peking University, Beijing, 100101, China; Corresponding author. Anhui Provincial Key Laboratory of High Field Magnetic Resonance Imaging, High Magnetic Field Laboratory, Hefei Institute of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.
Changlin Tian: Anhui Provincial Key Laboratory of High Field Magnetic Resonance Imaging, High Magnetic Field Laboratory, Hefei Institute of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China; School of Life Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230026, China; Corresponding author. Anhui Provincial Key Laboratory of High Field Magnetic Resonance Imaging, High Magnetic Field Laboratory, Hefei Institute of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.

Journal volume & issue: Vol. 3, no. 4
pp. 327 – 343

Abstract

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Proton nuclear (1H) is the observed nucleus on which most magnetic resonance imaging (MRI) applications depend. Most traditional 1H MRI can provide structural and functional information about organisms, while various non-proton nuclei (X-nuclei) MRI can provide more metabolic information. However, due to the relatively poor signal-to-noise ratio (SNR) of X-nuclei MRI, their applications are quite rare compared to 1H. Benefit from the rapid developments of MRI hardware and software technologies, X-nuclei MRI has recently attracted increasing interests in biomedical research. This review firstly introduces some current methods to improve the SNR of X-nuclei MRI. Secondly, this review describes biomedical applications of X-nuclei MRI, especially focusing on the current use of X-nuclei (13C, 17O, 19F, 23Na and 31P) MRI to study related diseases in different organs, including the brain, liver, kidney, heart and bone. Finally, perspectives studies on X-nuclei imaging and its potential applications are described in biomedical research.

Published in Magnetic Resonance Letters

ISSN: 2097-0048 (Print); 2772-5162 (Online)
Publisher: KeAi Communications Co. Ltd.
Country of publisher: China
LCC subjects: Science: Chemistry: Physical and theoretical chemistry; Science: Chemistry: Analytical chemistry
Website: https://www.keaipublishing.com/en/journals/magnetic-resonance-letters/

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