Nature Communications (Dec 2022)

An astrocytic signaling loop for frequency-dependent control of dendritic integration and spatial learning

  • Kirsten Bohmbach,
  • Nicola Masala,
  • Eva M. Schönhense,
  • Katharina Hill,
  • André N. Haubrich,
  • Andreas Zimmer,
  • Thoralf Opitz,
  • Heinz Beck,
  • Christian Henneberger

DOI
https://doi.org/10.1038/s41467-022-35620-8
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 17

Abstract

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How glial cells like astrocytes shape complex brain functions remains unclear. Here, the authors identified an astrocyte-mediated excitatory signaling loop between neurons and their own dendritic signal integration that supports spatial memory.