PO.1.1 Afimetoran, a potent and selective inhibitor of human toll-like receptor 7 (TLR7) and tlr8, provides robust efficacy in a murine lupus model of advanced disease

• A Rudra,
• H Qiu,
• R Zhang,
• S Dudhgaonkar,
• S Ranade,
• S Subramani,
• J Nagar,
• P Karunanithi,
• P Bhutani,
• V Kurawattimath,
• A Dyckman,
• G Schieven

Affiliations

A Rudra

1Centre for Intergrative Neuroscience and Neurodynamics, School of Psychology and Clinical Language Sciences, University of Reading, Reading, UK

H Qiu

1Department of Ophthalmology, Chinese PLA General Hospital, Beijing, China

R Zhang

1Section of Nephrology

S Dudhgaonkar

1Biocon Bristol Myers Squibb Research Center ~ Bangalore ~ India

S Ranade

1Biocon Bristol Myers Squibb Research Center ~ Bangalore ~ India

S Subramani

1Biocon Bristol Myers Squibb Research Center ~ Bangalore ~ India

J Nagar

1Biocon Bristol Myers Squibb Research Center ~ Bangalore ~ India

P Karunanithi

1Biocon Bristol Myers Squibb Research Center ~ Bangalore ~ India

P Bhutani

1Biocon Bristol Myers Squibb Research Center ~ Bangalore ~ India

V Kurawattimath

1Biocon Bristol Myers Squibb Research Center ~ Bangalore ~ India

A Dyckman

2Bristol Myers Squibb ~ Lawrenceville, New Jersey ~ USA

G Schieven

2Bristol Myers Squibb ~ Lawrenceville, New Jersey ~ USA