A stochastic assembly model for Nipah virus revealed by super-resolution microscopy

Qian Liu; Lei Chen; Hector C. Aguilar; Keng C. Chou

doi:10.1038/s41467-018-05480-2

Nature Communications (Aug 2018)

A stochastic assembly model for Nipah virus revealed by super-resolution microscopy

Qian Liu,
Lei Chen,
Hector C. Aguilar,
Keng C. Chou

Affiliations

Qian Liu: Department of Chemistry, University of British Columbia
Lei Chen: Department of Chemistry, University of British Columbia
Hector C. Aguilar: Department of Microbiology and Immunology, Cornell University
Keng C. Chou: Department of Chemistry, University of British Columbia

DOI: https://doi.org/10.1038/s41467-018-05480-2
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 7

Abstract

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The current model for Nipah virus assembly suggests that packaging is orchestrated by the matrix protein at the plasma membrane. Here, using super-resolution microscopy and Nipah virus-like particles, Liu et al. show that Nipah virus assembly is stochastic.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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