BIO Web of Conferences (Jan 2021)

Cacalia hastata L.: anti-influenza activity and phytochemical characteristics of extracts

  • Lobanova Irina,
  • Filippova Ekaterina,
  • Kotsupiy Olga,
  • Protsenko Maria,
  • Kharina Tatiana,
  • Mazurkova Natalia

DOI
https://doi.org/10.1051/bioconf/20213800073
Journal volume & issue
Vol. 38
p. 00073

Abstract

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This is the first study to assess antiviral activity against human influenza virus A/Aichi/2/68 and bird influenza virus A/chicken/Kurgan/05/2005 and phytochemical characteristics of an ethanol extract of Cacalia hastata L. from wild populations growing in the vicinity of Tomsk, Russia (mixed forest). A log10 neutralization index—an indicator of inhibition of virus replication by the extract from C. hastata leaves—was ≤2 lg for each influenza virus. The extract reduced the infectivity of the human influenza virus by 1.5-fold and that of the avian influenza virus by 1.7-fold. The phytochemical characterization of C. hastata (its various organs) showed that the largest amount of the tested biologically active substances is present in leaves and rhizomes.