Communications Biology (Jan 2023)

A high-throughput, 28-day, microfluidic model of gingival tissue inflammation and recovery

  • Ashley L. Gard,
  • Rebeccah J. Luu,
  • Ryan Maloney,
  • Madeline H. Cooper,
  • Brian P. Cain,
  • Hesham Azizgolshani,
  • Brett C. Isenberg,
  • Jeffrey T. Borenstein,
  • Jane Ong,
  • Joseph L. Charest,
  • Else M. Vedula

DOI
https://doi.org/10.1038/s42003-023-04434-9
Journal volume & issue
Vol. 6, no. 1
pp. 1 – 12

Abstract

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Microfluidic model of human gingival tissue with complex oral tissue architecture allows monthlong phenotypic expression, response and recovery to multiple inflammatory triggers and the potential for identification of new therapeutic targets for gum disease.