ANTIMICROBIAL SUSCEPTIBILITY SCREENING TEST OF MANN¬HEIMIA HAEMOLYTICA AND PASTEURELLA MULTOCIDA (SEROGROUP A) MOROCCAN STRAINS ISOLATED FROM RUMINANTS

Abstract

The present study is the first report aimed to determine the antibiotic susceptibility profiles of Mann-heimia haemolytica and Pasteurella multocida serogroup A Moroccan isolates. Each isolate was tested for sensitivity to amoxicillin (A), amoxicillin/clavulanic acid (AMC), gentamicin (CN), strep-tomycin (STR), florfenicol (FFC), doxycycline (DO), erythromycin (E), spiramycin (SP), nalidixic acid (NA), flumequine (UB), enrofloxacin (ENF) and sulfamethoxazole (SXT). All isolates showed resistance to the antibiotics tested at a rate greater than 14%, except for one P. multocida isolate which had no resistance profile against AMC. The highest level of resistance was found against NA for P. multocida (100%) and against UB (82.4%) for M. haemolytica. The sensitivity rates for P. multocida were between 0 (against NA) and 85.7% (against STR, AMC, FFC), whereas sensitivity of M. haemolytica isolates ranged from 17.6% against UB and 79.4% against AMC. For both Pas-teurellaceae species, the AMC was the most effective antimicrobial agent, however multi-drug resistance was observed in all isolates raising the interest to monitor the antimicrobial susceptibility of Pasteurellaceae species to determine appropriate antibiotic for treatment of pasteurellosis.

Keywords

• antibiotic susceptibility
• mannheimia haemolytica
• moroccan isolates
• pasteurella multocida