Chronic myelogenous leukemia in sickle cell/beta 0 -thalassemia

Abstract

Sickle cell/beta 0 -thalassemia (S/β0 -thal) is a compound heterozygous state for βS and β0 thalassemia. There are rare reported cases of patients with sickle cell disease who developed hematological neoplasms including myeloid and lymphoid conditions; however, to the best of our knowledge, chronic myelogenous leukemia (CML) occurring in S/β0 -thal has been reported in one case and this is the second such report.

Keywords

• chronic myelogenous leukemia
• sickle cell disease
• thalassemia