Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum (Apr 2008)
Relationship between Calcium, Phosphorous and Parathoromone with Calcification of Heart Valves In Dialyzed Patients In Qom, 1385-1386
Abstract
Background and ObjectivesMetastatic calcification is usually found in patients with chronic renal failure and hemodialyzed patients. Heart calcification becomes worse in hemodialyzed patients due to several factors. The aim of this study was to investigate relationship between Calcium, Phosphorous and Parathoromone(PTH) with calcification of heart valves in dialyzed patients. MethodsThis study is a Case- series study. 71 patients with calcification of heart valves who have referred for dialysis to Kamkar and Valiasr hospitals in Qom were selected as study population through echocardiography. Levels of Calcium, Phosphorous and PTH in the patients were assayed by suitable methods.ResultsOur results showed that in %17/5 of study population the level of calcium was higher than 10.4mg/dl, in %75.1 the level of PTH was higher than 70um/lit and finally the level of Phosphorous in %54.2 was higher than 4.5mg/dl.We concluded that there are a meaningful relationship between calcification of heart valves and levels of calcium, Phosphorous and PTH.ConclusionMeasurement of serum calcium, Phosphorous and PTH and performing echocardiography for prevention of calcification of heart valves are necessary in individuals who are dialyzed.Keywords: Heart Valves Calcification, Calcium, PTH, Phosphorous