Nature Communications (May 2022)

Seeking patterns of antibiotic resistance in ATLAS, an open, raw MIC database with patient metadata

  • Pablo Catalán,
  • Emily Wood,
  • Jessica M. A. Blair,
  • Ivana Gudelj,
  • Jonathan R. Iredell,
  • Robert E. Beardmore

DOI
https://doi.org/10.1038/s41467-022-30635-7
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 15

Abstract

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Pathogens are typically classified as ‘antibiotic-resistant’ for clinical purposes based on cut-off values of minimum inhibitory concentrations (MICs). In this study, the authors explore quantitative values of MICs using the global ‘ATLAS’ database of pathogen-antibiotic pairs, describe trends in resistance, and compare results to other antibiotic resistance surveillance data.