An Indian Tertiary Care Hospital Scenario of Papillary Carcinoma of Thyroid

Abstract

Introduction: Thyroid carcinoma is the most common endocrine malignancy and its Papillary Histotype {Papillary Carcinoma of Thyroid (PTC)} is the most common type of Thyroid cancer. The clinicopathological features of PTC vary with geographical location. Aim: To describe the clinicopathological profile of PTC in a Tertiary Care Hospital located in Chennai, Tamil Nadu, India. Materials and Methods: Data on age, sex, centricity of the tumour, presence of calcifications, infiltration, metastasis, associated non malignant conditions and frequency of histological subtypes of all cases of PTC diagnosed in Department of Pathology, Madras Medical College Chennai, Tamil Nadu, India between January 2007 and December 2011 were obtained from clinicopathological documents and analysed statistically. Results: Statistically significant correlations were found between age and sex, age and metastasis, sex and centricity, sex and metastasis, size of lesion and sex, size of lesion and age, size and presence of calcifications and presence of calcifications and metastasis. Conclusion: Scenario of PTC in our tertiary care setup which warrants attention is male preponderance of multicentric lesions. Further, a high association with colloid nodular goitre, while low incidence of tall cell variant is notable clinico pathological scenarios in this study.

Keywords

• calcifications
• centricity
• clinicopathological features
• metastasis
• tall cell variant