A SPECTRUM OF CARBOHYDRATE SPECIFICITY OF RECEPTORS OF ADHESION OF VIBRIO CHOLERAE NON-O1, NON-O139

Abstract

Purpose: revealing of the fullest spectrum of specificity lectin receptors strains of Vibrio cholerae non-O1, non-O139, participating in adgesion mechanisms, on model of agglutination of erythrocytes in reaction of competitive ingibition.Materials and methods: in work are used strains of Vibrio cholerae non-O1, non-O139, isolated from objects of environment and from people. Spectrum lectin receptors defined in inhibition reaction hemagglutination.Results: it is revealed, that strains of Vibrio cholerae non-O1, non-O139, irrespective of object of allocation possess weak ability to agglutination of erythrocytes that correlates with low adhesion. Low ability to agglutination is caused astable by an expression of adhesins (lectin receptors) various specificity. Ability to an expression of receptors of very wide spectrum, coming to light on a wide spectrum of different kinds of erythrocytes.Summary: at strains of Vibrio cholerae non-O1, non-O139 it is not revealed distinctions in specificity lectin receptors depending on an accessory to serogroupe, toxigenic, object of isolation.

Keywords

• vibrio cholerae non-o1
• non-o139
• adhesion
• hemagglutination
• lectin receptors