Medical Mycology Case Reports (Jun 2023)

Human protothecosis: A case report in northeastern Brazil

  • Daniel Wagner de Castro Lima Santos,
  • Yankee Costa Magalhaes Diniz,
  • Raimunda Ribeiro da Silva,
  • Sirlei Garcia Marques,
  • Maria Rosa Quaresma Bomfim,
  • Conceição de Maria Pedrozo e Silva de Azevedo

Journal volume & issue
Vol. 40
pp. 1 – 4

Abstract

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We describe a case of extensive human cutaneous protothecosis in the northeastern of Brazil. The diagnosis was made through histopathological examination of skin samples and culturing on Sabouraud dextrose agar, with identification through mass spectrometry. Treatment with itraconazole failed and was switched to liposomal amphotericin followed by voriconazole with clinical cure. Prothotecosis should be a diagnostic hypothesis when there are skin lesions after trauma, specially in situations of atypical evolution.

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