International Medical Case Reports Journal (Dec 2023)
Birdshot Chorioretinopathy in Early Adulthood: Review of Current Literature and Case Report
Abstract
Brandon Huy Pham,1 Gunay Uludag,2 Doan Luong Hien,2 Ngoc Trong Tuong Than,2 Jaclyn Joyce Hwang,2 Amir Akhavanrezayat,2 Wataru Matsumiya,2 Sherin Lajevardi,2 Jonathan Regenold,2 Muhammad Sohail Halim,2 Quan Dong Nguyen2 1Stanford University School of Medicine, Palo Alto, CA, USA; 2Spencer Center for Vision Research, Byers Eye Institute at Stanford University, Palo Alto, CA, USACorrespondence: Quan Dong Nguyen, Spencer Center for Vision Research, Byers Eye Institute at Stanford, 2370 Watson Court, Suite 200, Palo Alto, CA, 94303, USA, Tel +1 650-725-7245, Email [email protected]: We describe the course of a patient diagnosed with birdshot chorioretinopathy (BSCR) in early adulthood and summarize clinical findings from similar BSCR patients reported in the literature.Observations: A 37-year-old male presented to our tertiary uveitis facility with bilateral ocular discomfort, hazy vision, and floaters. Ocular examination was notable for vitritis, optic disc edema, and ovoid hypopigmented chorioretinal lesions, visible on indocyanine green chorioangiography as multiple hypocyanescent spots in the intermediate phase. Full-field electroretinography and visual evoked potential showed global retinal dysfunction and optic nerve dysfunction. Laboratory evaluations were notable only for human leukocyte antigen (HLA)-A29 positivity. The patient was diagnosed with BSCR and started on oral prednisone and eventually managed with infliximab.Conclusions and Importance: BSCR can affect patients in early adulthood. Proper diagnostic work-up, including assessing HLA-A29 positivity, is needed to manage atypical cases.Keywords: birdshot chorioretinopathy, early adulthood, human leukocyte antigen (HLA)-A29
