Using Cartesian Doubt To Build a Sequencing-Based View of Microbiology

Braden T. Tierney; Erika Szymanski; James R. Henriksen; Aleksandar D. Kostic; Chirag J. Patel

doi:10.1128/mSystems.00574-21

mSystems (Oct 2021)

Using Cartesian Doubt To Build a Sequencing-Based View of Microbiology

Braden T. Tierney,
Erika Szymanski,
James R. Henriksen,
Aleksandar D. Kostic,
Chirag J. Patel

Affiliations

Braden T. Tierney: ORCiD; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA
Erika Szymanski: ORCiD; Department of English, Colorado State University, Fort Collins, Colorado, USA
James R. Henriksen: ORCiD; Mr. Fusion Inc., Fort Collins, Colorado, USA
Aleksandar D. Kostic: ORCiD; Section on Pathophysiology and Molecular Pharmacology, Joslin Diabetes Center, Boston, Massachusetts, USA
Chirag J. Patel: ORCiD; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA

DOI: https://doi.org/10.1128/mSystems.00574-21
Journal volume & issue: Vol. 6, no. 5

Abstract

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The technological leap of DNA sequencing generated a tension between modern metagenomics and historical microbiology. We are forcibly harmonizing the output of a modern tool with centuries of experimental knowledge derived from culture-based microbiology.

Published in mSystems

ISSN: 2379-5077 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/msystems

About the journal