Therapeutic Advances in Neurological Disorders (Feb 2021)

Extensive cerebellar involvement and cognitive impairment in COVID-19-associated acute necrotizing encephalopathy

  • Dumitru Ciolac,
  • Igor Crivorucica,
  • Eremei Zota,
  • Nadejda Gorincioi,
  • Daniela Efremova,
  • Diana Manea,
  • Veaceslav Crivorucica,
  • Mihail Ciocanu,
  • Stanislav A. Groppa

DOI
https://doi.org/10.1177/1756286420985175
Journal volume & issue
Vol. 14

Abstract

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Neurological complications of the newly appeared severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are increasingly recognized. Here, we report a case of a young male presenting with a clinical and neuroimaging scenario of an acute necrotizing encephalopathy related to the coronavirus disease 2019 (COVID-19). This case is notable by its distinct pattern of magnetic resonance imaging findings of an extensive involvement of the cerebellum, and emergence of cognitive and behavioral impairment.