Cancer Management and Research (Jun 2024)
Sign of Neck Mass as the Chief Complaint: A Case Report and Literature Review About Thyroid Metastasis of Colorectal Cancer
Abstract
Zhaorui Wang,1 Jingjing Wang,1 Jing Pei,2 Yubo Pan,2 Rui Ding1 1Department of Emergency Surgery, Lu ‘an People’s Hospital, Lu ‘an Hospital Affiliated to Anhui Medical University, Lu ‘an, Anhui, 237000, People’s Republic of China; 2Department of General Surgery, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230022, People’s Republic of ChinaCorrespondence: Rui Ding, Department of Emergency Surgery, Lu ‘an People’s Hospital, Lu ‘an Hospital Affiliated to Anhui Medical University, No. 21, Wanxi West Road, Lu ‘an, Anhui, 237000, People’s Republic of China, Email [email protected]: Commonly, the thyroid gland is regarded as an organ with fewer metastatic diseases, and colorectal metastasis to the thyroid (CMT) is rarely reported, especially, with that the clinical sign of thyroid metastasis nidus is the chief complaint. The CMT occurs in advanced colorectal cancer and is associated with poor prognosis and short survival.Case Report: In this case, we reported a patient with the sign of neck mass as the first manifestation of CMT. The patient underwent a partial thyroidectomy in June 2019, immunohistochemical findings of thyroid carcinoma suggested the possibility of adenocarcinoma of gastrointestinal tract. The patient underwent a colonoscopy in July 2019 and a colonic mass was found. Pathological examination diagnosed rectal adenocarcinoma. The patient underwent neoadjuvant chemotherapy, surgical treatment, postoperative adjuvant chemotherapy and targeted therapy. The patient died in June 2022.Conclusion: The metastasis disease would not be ignored at all, when a patient complains at signs of neck mass. Further, the possibility of metastasis cancer should be considered once thyroid nodules occur in patients with colorectal cancer. Even though the biological characteristics and stage of the primary tumor have an important impact on the prognosis, positive standardized treatments can also be helpful.Keywords: colorectum cancer metastases, secondary thyroid cancer, neck mass, case report, therapy, prognosis