Frontiers in Pharmacology (Jun 2022)
Integration of Non-Targeted Metabolomics and Targeted Quantitative Analysis to Elucidate the Synergistic Antidepressant Effect of Bupleurum Chinense DC-Paeonia Lactiflora Pall Herb Pair by Regulating Purine Metabolism
- Jiajun Chen,
- Jiajun Chen,
- Jiajun Chen,
- Tian Li,
- Tian Li,
- Tian Li,
- Xuemei Qin,
- Xuemei Qin,
- Xuemei Qin,
- Guanhua Du,
- Guanhua Du,
- Yuzhi Zhou,
- Yuzhi Zhou,
- Yuzhi Zhou
Affiliations
- Jiajun Chen
- Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan, China
- Jiajun Chen
- The Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Shanxi University, Taiyuan, China
- Jiajun Chen
- The Key Laboratory of Effective Substances Research and Utilization in TCM of Shanxi Province, Taiyuan, China
- Tian Li
- Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan, China
- Tian Li
- The Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Shanxi University, Taiyuan, China
- Tian Li
- The Key Laboratory of Effective Substances Research and Utilization in TCM of Shanxi Province, Taiyuan, China
- Xuemei Qin
- Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan, China
- Xuemei Qin
- The Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Shanxi University, Taiyuan, China
- Xuemei Qin
- The Key Laboratory of Effective Substances Research and Utilization in TCM of Shanxi Province, Taiyuan, China
- Guanhua Du
- Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan, China
- Guanhua Du
- Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
- Yuzhi Zhou
- Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan, China
- Yuzhi Zhou
- The Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Shanxi University, Taiyuan, China
- Yuzhi Zhou
- The Key Laboratory of Effective Substances Research and Utilization in TCM of Shanxi Province, Taiyuan, China
- DOI
- https://doi.org/10.3389/fphar.2022.900459
- Journal volume & issue
-
Vol. 13
Abstract
Graphical Abstract
Keywords
- Bupleurum chinense DC-Paeonia lactiflora Pall
- compatibility mechanism
- depression
- cortex
- xanthine
- oxidative stress
