PLoS ONE (Jan 2022)

Comparison of arterial and venous allograft bypass in chronic limb-threatening ischemia.

  • Dávid Garbaisz,
  • Péter Osztrogonácz,
  • András Mihály Boros,
  • László Hidi,
  • Péter Sótonyi,
  • Zoltán Szeberin

DOI
https://doi.org/10.1371/journal.pone.0275628
Journal volume & issue
Vol. 17, no. 10
p. e0275628

Abstract

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IntroductionFemoro-popliteal bypass with autologous vascular graft is a key revascularization method in chronic limb-threatening ischemia (CLTI). However, the lack of suitable autologous conduit may occur in 15-45% of the patients, necessitating the implantation of prosthetic or allogen grafts. Only little data is available on the outcome of allograft use in CLTI.AimsOur objective were to evaluate the long term results of infrainguinal allograft bypass surgery in patients with chronic limb-threatening ischemia (CLTI) and compare the results of arterial and venous allografts.MethodsSingle center, retrospective study analysing the outcomes of infrainguinal allograft bypass surgery in patients with CLTI between January 2007 and December 2017.ResultsDuring a 11-year period, 134 infrainguinal allograft bypasses were performed for CLTI [91 males (67.9%)]. Great saphenous vein (GSV) was implanted in 100 cases, superficial femoral artery (SFA) was implanted in 34 cases. Early postoperative complications appeared in 16.4% of cases and perioperative mortality (ConclusionAllograft implantation is a suitable method for limb salvage in CLTI. The patency of arterial allograft is better than venous allograft patency, especially in below-knee position during infrainguinal allograft bypass surgery.