Canadian Journal of Infectious Diseases (Jan 1990)

Non-Beta-Lactamase-Producing Penicillin-Resistant Enterococcus faecium in a Clinical Setting

  • Daniel Eymard,
  • Andre Dascal,
  • John Hiscott,
  • Sonia Gioseffini,
  • Janet Stevenson,
  • Joseph Portnoy,
  • Jack Mendelson

DOI
https://doi.org/10.1155/1990/252859
Journal volume & issue
Vol. 1, no. 3
pp. 73 – 76

Abstract

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Six clinical isolates of Enterococcus faecium highly resistant to penicillin are reported. These strains did not produce beta-lactamase and no plasmid DNA could be detected. It is postulated that the mechanism of resistance is one or more chromosomally mediated alterations of penicillin-binding proteins.