Metabolic syndrome and cerebrovascular disorders

Abstract

A combination of a number of risk factors, known as metabolic syndrome (MS), leads to fast progression of vascular diseases and the development of severe complications. Earlier we showed that abnormalities of the system of hemorheology and hemostasis accompanying MS played a significant role in the development of ischemic stroke. In this report we present three clinical cases of combination of MS with various forms of ischemic cerebrovascular pathology, including description of a patient who underwent surgical treatment because of a severe stenotic process in brachiocephal arteries. Shown is the effect of MS on different pathogenic constituents of vascular disorders, including the system of hemorheology and hemostasis. The necessity for complex therapy of main manifestations of MS in acute and chronic cerebrovascular disorders is grounded.

Keywords

• metabolic syndrome
• cerebrovascular disorders
• pathogenesis
• treatment