Bioinformatics and Biology Insights (Jan 2008)

IMAGE: A New Tool for the Prediction of Transcription Factor Binding Sites

  • R. Casilli,
  • A. Marongiu,
  • S. Melchionna,
  • P. Palazzari,
  • R. Paparcone,
  • V. Rosato

Journal volume & issue
Vol. 2
pp. 363 – 373

Abstract

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IMAGE is an application tool, based on the vector quantization method, aiding the discovery of nucleotidic sequences corresponding to Transcription Factor binding sites. Starting from the knowledge of regulation regions of a number of co-expressed genes, the software is able to predict the occurrence of specific motifs of different lengths (starting from 6 base pairs) with a defined number of punctual mutations.