P12.10 In vivo dynamics and anti-tumor effects of B7-H3-directed CAR T-cells in an orthotopic medulloblastoma mouse model

• DH Busch,
• N Thon,
• K Muller,
• S Langer,
• L von Baumgarten,
• C Eberle,
• V Buschinger,
• VR Buchholz,
• J Blobner,
• L Dengler,
• JJ Herold,
• N Teske,
• P Karschnia,
• NN Kutlu,
• E Nikolaishvili,
• L Warmuth,
• JC Tonn,
• T Feuchtinger

Affiliations

DH Busch

Aff5 grid.6936.a0000000123222966Institut für Medizinische Mikrobiologie Immunologie und HygieneTechnische Universität München Munich Germany

N Thon

3University Hospital of Munich, Neurosurgery, Munich, Germany

K Muller

6Department of Neurology, University Hospital, LMU Munich, Munich, Germany

S Langer

Institute of Human Genetics, Technical University München and GSF, Neuherberg, Germany

L von Baumgarten

3Department of Neurology, University Hospital, LMU Munich, Munich, Germany

C Eberle

1University Hospital of the Ludwig-Maximilians University Munich (LMU), Munich, Germany

V Buschinger

6Institute for Medical Microbiology, Immunology and Hygiene, TU Munich, Munich, Germany

VR Buchholz

6Institute for Medical Microbiology, Immunology and Hygiene, TU Munich, Munich, Germany

J Blobner

1University Hospital of the Ludwig-Maximilians University Munich (LMU), Munich, Germany

L Dengler

1University Hospital of the Ludwig-Maximilians University Munich (LMU), Munich, Germany

JJ Herold

1Department of Neurosurgery, University Hospital of the Ludwig-Maximilians-University Munich, Munich, Germany, München, Germany

N Teske

1University Hospital of the Ludwig-Maximilians University Munich (LMU), Munich, Germany

P Karschnia

1University Hospital of the Ludwig-Maximilians University Munich (LMU), Munich, Germany

NN Kutlu

2Department of Pediatric Hematology, Oncology, Hemostaseology and Stem Cell Transplantation Dr. von Hauner Children’s Hospital, University Hospital of the Ludwig- Maximilians-University Munich, Munich, Germany, München, Germany

E Nikolaishvili

1Department of Neurosurgery, University Hospital of the Ludwig-Maximilians-University Munich, Munich, Germany, München, Germany

L Warmuth

4Institute for Medical Microbiology, Immunology and Hygiene, Technische Universitaet Muenchen (TUM), Munich, Germany, München, Germany

JC Tonn

1Department of Neurosurgery, University Hospital of the Ludwig-Maximilians-University Munich, Munich, Germany, München, Germany

T Feuchtinger

2Department of Pediatric Hematology, Oncology, Hemostaseology and Stem Cell Transplantation Dr. von Hauner Children’s Hospital, University Hospital of the Ludwig- Maximilians-University Munich, Munich, Germany, München, Germany