714 PD1 x TGFβR2 bispecifics selectively block TGFβR2 on PD1-positive T cells, promote T cell activation, and elicit an anti-tumor response in solid tumors

• Gregory Moore,
• Lukasz Ochyl,
• Christine Bonzon,
• Seung Chu,
• Rumana Rashid,
• John Desjarlais,
• Kendra Avery,
• Suzanne Schubbert,
• Erik Pong,
• Alex Nisthal,
• James Ernst

Affiliations

Gregory Moore

Xencor, Inc., Monrovia, CA, USA

Lukasz Ochyl

Aff442 grid.214458.e0000000086837370University of Michigan Ann Arbor MI USA

Christine Bonzon

Aff390 Xencor, Inc. Monrovia CA USA

Seung Chu

Aff390 Xencor, Inc. Monrovia CA USA

Rumana Rashid

Aff390 Xencor, Inc. Monrovia CA USA

John Desjarlais

Aff390 Xencor, Inc. Monrovia CA USA

Kendra Avery

Xencor, Inc., Monrovia, CA, USA

Suzanne Schubbert

Xencor, Inc., Monrovia, CA, USA

Erik Pong

Xencor, Inc., Monrovia, CA, USA

Alex Nisthal

Xencor, Inc., Monrovia, CA, USA

James Ernst

Xencor, Inc., Monrovia, CA, USA