Evaluation of antioxidant activity and phenolic compounds content in methanol extract obtained from leaves Commiphora Myrrha

Abstract

This work presents shows the study of antioxidant activity and quantification of phenolic content determined for the methanol extract obtained from Commiphora myrrha. The high content of phenolic compounds were evaluated against the potential to sequester free radical through the model 2,2-diphenyl-1-picrizil hydrazyl (DPPH) and compared with a standard rutin. The results show that the inhibitory capacity of the extract (IC50) was 0.21 mg.L-1. The extract pursued an antioxidant activity of 91.3% compared to the scavenging ability of rutin standard. The content of phenolic extract was assessed by using the Folin-Ciocalteu determined where the IC50 was 3,02 mg.L-1. The concentration of total phenols was determined 1.176 ± 0.263 mg gallic acid equivalent . g-1 of extract (n=5). The results show that extracts of C. myrrha have high antioxidant potential and additional studies are needed for isolation, characterization and use of their property in pharmaceutical, nutritinal and cosmetology.

Keywords

• Antioxidant activity
• Phenolic compounds
• DPPH
• IC50