Kinetics and magnitude of viral RNA shedding as indicators for Influenza A virus transmissibility in ferrets

Joanna A. Pulit-Penaloza; Nicole Brock; Jessica A. Belser; Xiangjie Sun; Claudia Pappas; Terrence M. Tumpey; Taronna R. Maines

doi:10.1038/s42003-023-04459-0

Communications Biology (Jan 2023)

Kinetics and magnitude of viral RNA shedding as indicators for Influenza A virus transmissibility in ferrets

Joanna A. Pulit-Penaloza,
Nicole Brock,
Jessica A. Belser,
Xiangjie Sun,
Claudia Pappas,
Terrence M. Tumpey,
Taronna R. Maines

Affiliations

Joanna A. Pulit-Penaloza: Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention
Nicole Brock: Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention
Jessica A. Belser: Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention
Xiangjie Sun: Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention
Claudia Pappas: Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention
Terrence M. Tumpey: Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention
Taronna R. Maines: Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention

DOI: https://doi.org/10.1038/s42003-023-04459-0
Journal volume & issue: Vol. 6, no. 1
pp. 1 – 10

Abstract

Read online

The analysis of viral RNA shedding and emission dynamics for 14 diverse influenza viruses in ferrets reveals that efficient ferret-to-ferret transmission via air is directly associated with robust emission of virus-laden particles at early times.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

About the journal