Journal of Nanobiotechnology (Feb 2022)
Thermo/pH dual-responsive micelles based on the host–guest interaction between benzimidazole-terminated graft copolymer and β-cyclodextrin-functionalized star block copolymer for smart drug delivery
Abstract
Highlights Thermo/pH dual-responsive micelles were formed in an aqueous solution based on host–guest interaction. The release of DOX was facilitated in acidic conditions and at temperatures above the LCST of the micelles. The drug-loaded micelles displayed higher antitumor activity than free DOX.
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