Problems in the diagnosis of acute kidney injury in patients with ST-segment elevation myocardial infarction

Abstract

AIM: To estimate the frequency and severity of acute kidney injury (AKI) in patients with ST-segment elevation acute myocardial infarction (STSEAMI), to specify whether the changes in diuresis and serum creatinine levels are equally sensitive diagnostic criteria for AKI, and to define their prognostic value/MATERIAL AND METHODS: Three hundred and nineteen patients (249 (78%) men and 70 (22%) women; age 58±10 years) with STSEAMI who received thrombolytic therapy (TLT) were examined. The diagnosis of STSEAMI, indications for and contraindications to TLT, evaluation of its efficiency were made in accordance with the All-Russian Scientific Society of Cardiology guidelines (2007). AKI was diagnosed and classified using the KDIGO guidelines (2012)/RESULTS: AKI was diagnosed in terms of diuresis, calculated creatinine levels, and creatinine level changes in 107 (34%), 73 (23%), and 68 (22%) patients, respectively. Among the patients with AKI diagnosed in view of diuresis, in-hospital death rates were higher than in those without AKI (ξ2=25.46; p

Keywords

• acute kidney injury
• st-segment elevation acute myocardial infarction
• kdigo guidelines
• calculated creatinine