European Journal of Case Reports in Internal Medicine (Jan 2024)

Challenges in diagnosing post-splenectomy cytomegalovirus mononucleosis

  • Kim Abbegail Tan Aldecoa,
  • Rahul Pidikiti,
  • Jaisal Brar,
  • Geetha Krishnamoorthy,
  • Shamla Kalyan,
  • Cecilia Cosma,
  • Pritha Chitagi

DOI
https://doi.org/10.12890/2024_004263

Abstract

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Cytomegalovirus (CMV) infection is often asymptomatic. However, in certain individuals, it can cause non-specific signs and symptoms that maybe hard to recognise. The condition may therefore be overlooked or misdiagnosed, leading to prolonged illness and serious sequelae. In this case report, we present a rare instance of CMV infection in an HIV-negative patient who had a remote history of splenectomy and was experiencing prolonged fever and markedly elevated white blood cell (WBC) count.

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