Genome comparison of Listeria monocytogenes serotype 4a strain HCC23 with selected lineage I and lineage II L. monocytogenes strains and other Listeria strains

Debarati Paul; Chelsea Steele; Janet R. Donaldson; Michelle M. Banes; Ranjit Kumar; Susan M. Bridges; Mark Arick II; Mark L. Lawrence

doi:10.1016/j.gdata.2014.06.010

Genomics Data (Dec 2014)

Genome comparison of Listeria monocytogenes serotype 4a strain HCC23 with selected lineage I and lineage II L. monocytogenes strains and other Listeria strains

Debarati Paul,
Chelsea Steele,
Janet R. Donaldson,
Michelle M. Banes,
Ranjit Kumar,
Susan M. Bridges,
Mark Arick II,
Mark L. Lawrence

Affiliations

Debarati Paul: Amity Institute of Biotechnology, Amity University, Noida, India
Chelsea Steele: College of Veterinary Medicine, Mississippi State University, Mississippi State, MS, USA
Janet R. Donaldson: Department of Biological Sciences, Mississippi State University, Mississippi State, MS, USA
Michelle M. Banes: College of Veterinary Medicine, Mississippi State University, Mississippi State, MS, USA
Ranjit Kumar: College of Veterinary Medicine, Mississippi State University, Mississippi State, MS, USA
Susan M. Bridges: Department of Computer Sciences and Engineering, Mississippi State University, Mississippi State, MS, USA
Mark Arick II: Institute for Genomics, Biocomputing, and Biotechnology, Mississippi State University, Mississippi State, MS, USA
Mark L. Lawrence: College of Veterinary Medicine, Mississippi State University, Mississippi State, MS, USA

DOI: https://doi.org/10.1016/j.gdata.2014.06.010
Journal volume & issue: Vol. 2, no. C
pp. 219 – 225

Abstract

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More than 98% of reported human listeriosis cases are caused by specific serotypes within genetic lineages I and II. The genome sequence of Listeria monocytogenes lineage III strain HCC23 (serotype 4a) enables whole genomic comparisons across all three L. monocytogenes lineages. Protein cluster analysis indicated that strain HCC23 has the most unique protein pairs with nonpathogenic species Listeria innocua. Orthology analysis of the genome sequences of representative strains from the three L. monocytogenes genetic lineages and L. innocua (CLIP11262) identified 319 proteins unique to nonpathogenic strains HCC23 and CLIP11262 and 58 proteins unique to pathogenic strains F2365 and EGD-e. BLAST comparison of these proteins with all the sequenced L. monocytogenes and L. innocua revealed 126 proteins unique to serotype 4a and/or L. innocua; 14 proteins were only found in pathogenic serotypes. Some of the 58 proteins unique to pathogenic strains F2365 and EGD-e were previously published and are already known to contribute to listerial virulence.

Published in Genomics Data

ISSN: 2213-5960 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Science: Biology (General): Genetics
Website: http://www.journals.elsevier.com/genomics-data/

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