Skin lesion at acute monoblastic leukemia (clinical observation)

Abstract

At present diagnosis of acute leukemia does not represent any difficulties and is based on morphological and immunophenotypical bone marrow studies. The paper presents a non-standard verification algorithm of acute monoblastic leukemia in elderly female patient, with leukemic skin lesion. Morphologic and immunohistochemical studies of biopsy materials of skin, lymph node and bone marrow allow establishing a linear membership of tumor cells and promptly verifying the diagnosis of leukemia. Lack of the overall clinical examination in such cases leads to diagnostic errors and to late verification of the true diagnosis and significantly worsens the prognosis.

Keywords

• острый монобластный лейкоз
• экстрамедуллярные очаги поражения
• лейкемическое поражение кожи
• acute monoblastic leukemia
• extramedullar lesions
• leukemic skin lesion