Idiopathic CD4 lymphocytopenia with giant cell arteritis and pulmonary mucormycosis

Ryan A. Denu; Patrick S. Rush; Sarah E. Ahrens; Ryan P. Westergaard

doi:10.1016/j.mmcr.2014.10.002

Medical Mycology Case Reports (Oct 2014)

Idiopathic CD4 lymphocytopenia with giant cell arteritis and pulmonary mucormycosis

Ryan A. Denu,
Patrick S. Rush,
Sarah E. Ahrens,
Ryan P. Westergaard

Affiliations

Ryan A. Denu: Medical Scientist Training Program, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
Patrick S. Rush: Department of Pathology and Laboratory Medicine, University of Wisconsin Hospital and Clinics, Madison, WI, USA
Sarah E. Ahrens: Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
Ryan P. Westergaard: Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA

DOI: https://doi.org/10.1016/j.mmcr.2014.10.002
Journal volume & issue: Vol. 6, no. C
pp. 73 – 75

Abstract

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Idiopathic CD4 lymphocytopenia (ICL) is characterized by a low CD4+ lymphocyte count in the absence of HIV or other underlying etiologies. We report a case of a 57-year old man with ICL and giant cell arteritis (GCA) who developed pulmonary mucormycosis, which, to our knowledge, is the first report of these occurring in a patient with ICL. Abnormally low total lymphocyte or CD4+ cell counts occurring in patients with autoimmune disorders should alert clinicians to the possibility of ICL. Immunosuppressive treatment should be used with caution in this context.

Published in Medical Mycology Case Reports

ISSN: 2211-7539 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Medicine (General); Science: Biology (General)
Website: https://www.journals.elsevier.com/medical-mycology-case-reports/

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