Morphological Changes Providing Adhesion of Detached Retina After Laser Coagulation

Abstract

Purpose. Experimental study the morphological changes of the retina and choroid, providing adhesion of the detached retina in the first 72 hours after laser coagulation.Material and methods. A clinical and morphological study of 12 eyes of 12 Chinchilla rabbits with experimentally simulated retinal detachment was performed 12, 24, 48 and 72 hours after the operation of transciliary vitrectomy with laser coagulation.Results. Due to local destruction and exudative effects in the field of laser coagulation of the retina (increasing to 24 hours and decreasing to 72 hours) detected the formation of a tight adhesive contact between the shells resulting from the destruction of exudative fibrinogen and deposition fibrin. Histological changes in the retina and choroid in the area of laser coagulation in the first two days corresponded to the growing destructive-exudative phase of fibrinoid’s inflammation moderate with maximum cases in the period of 48 hours with the attenuation of exudative effects and proliferative phase after 72 hours.Conclusion. In the period from 24 to 48 hours of the adhesive after laser coagulation is formed of a dense chorioretinal contact by deposits of fibrin, which serves as a fibrinogen serum, part extravasal exudate area of laser coagulation. Based on the studied morphological processes, it can be assumed that chorioretinal adhesion in the LC area becomes strong enough to independently hold the retina in place 48 hours after surgery.

Keywords

• vitrectomy
• laser coagulation
• chorioretinal adhesion