APOE3 Christchurch modulates β-catenin/Wnt signaling in iPS cell-derived cerebral organoids from Alzheimer’s cases

• Paula Perez-Corredor,
• Timothy E. Vanderleest,
• Guido N. Vacano,
• Justin S. Sanchez,
• Nelson D. Villalba-Moreno,
• Claudia Marino,
• Susanne Krasemann,
• Miguel A. Mendivil-Perez,
• David Aguillón,
• Marlene Jiménez-Del-Río,
• Ana Baena,
• Diego Sepulveda-Falla,
• Francisco Lopera,
• Yakeel T. Quiroz,
• Yakeel T. Quiroz,
• Yakeel T. Quiroz,
• Joseph F. Arboleda-Velasquez,
• Randall C. Mazzarino

Affiliations

Paula Perez-Corredor

Schepens Eye Research Institute of Mass Eye and Ear and Department of Ophthalmology at Harvard Medical School, Boston, MA, United States

Timothy E. Vanderleest

Schepens Eye Research Institute of Mass Eye and Ear and Department of Ophthalmology at Harvard Medical School, Boston, MA, United States

Guido N. Vacano

Vacano Informatics LLC, Arvada, CO, United States

Justin S. Sanchez

Massachusetts General Hospital and Department of Neurology at Harvard Medical School, Boston, MA, United States

Nelson D. Villalba-Moreno

Molecular Neuropathology of Alzheimer’s Disease, Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

Claudia Marino

Schepens Eye Research Institute of Mass Eye and Ear and Department of Ophthalmology at Harvard Medical School, Boston, MA, United States

Susanne Krasemann

Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

Miguel A. Mendivil-Perez

The Neuroscience Group of Antioquia, University of Antioquia, Medellı́n, Colombia

David Aguillón

The Neuroscience Group of Antioquia, University of Antioquia, Medellı́n, Colombia

Marlene Jiménez-Del-Río

The Neuroscience Group of Antioquia, University of Antioquia, Medellı́n, Colombia

Ana Baena

The Neuroscience Group of Antioquia, University of Antioquia, Medellı́n, Colombia

Diego Sepulveda-Falla

Molecular Neuropathology of Alzheimer’s Disease, Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

Francisco Lopera

The Neuroscience Group of Antioquia, University of Antioquia, Medellı́n, Colombia

Yakeel T. Quiroz

Massachusetts General Hospital and Department of Neurology at Harvard Medical School, Boston, MA, United States

Yakeel T. Quiroz

The Neuroscience Group of Antioquia, University of Antioquia, Medellı́n, Colombia

Yakeel T. Quiroz

Massachusetts General Hospital and Department of Psychiatry at Harvard Medical School, Boston, MA, United States

Joseph F. Arboleda-Velasquez

Schepens Eye Research Institute of Mass Eye and Ear and Department of Ophthalmology at Harvard Medical School, Boston, MA, United States

Randall C. Mazzarino

Schepens Eye Research Institute of Mass Eye and Ear and Department of Ophthalmology at Harvard Medical School, Boston, MA, United States