Journal of Microbiology, Immunology and Infection (Oct 2021)
Evaluation of six anti-SARS-CoV-2 antibody test kits and practical approaches to optimize the diagnostic performance
Abstract
In an investigation of six anti-SARS-CoV-2 antibody kits with different target antigen and methodology, each kit showed comparable performance. As false-positive reactions occurred independently with different kits, specificity increased to 100% when pairs of kits were used. With three-kit combination, both sensitivity (99.1%) and specificity (100%) increased.