Nature Communications (Aug 2020)

Experience-dependent resonance in amygdalo-cortical circuits supports fear memory retrieval following extinction

  • Minagi Ozawa,
  • Patrick Davis,
  • Jianguang Ni,
  • Jamie Maguire,
  • Thomas Papouin,
  • Leon Reijmers

DOI
https://doi.org/10.1038/s41467-020-18199-w
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 16

Abstract

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Theta range oscillations in the basolateral amygdala (BLA) and the medial prefrontal cortex (mPFC) are associated with conditioned fear. Here, the authors use exogenous oscillatory stimulation of the BLA and mPFC in mice to determine the dynamic roles of theta-range oscillatory states across conditioned fear and extinction learning.